For two other substances, the MSC acknowledged that there is scientific evidence that 4-tert-butylphenol(PTBP), also proposed by Germany, is an endocrine disruptor, and that benzene-1,2,4-tricarboxylic acid 1,2-anhydride (trimellitic anhydride, TMA), proposed by the Netherlands, is a respiratory sensitiser. For both, the majority of the members concluded, based on the overall assessment of all factors that the information provided is sufficient to constitute an equivalent level of concern to carcinogenic, mutagenic, toxic to reproduction (CMRs category 1A or 1B); persistent, bioaccumulative and toxic (PBT) and very persistent and very bioaccumulative (vPvB) substances. A few members, however, had different views.
As no unanimous agreement was reached by the MSC on the SVHC identification of PTBP and TMA, ECHA will submit the MSC opinions and the minority positions on these two substances to the European Commission. The Commission subsequently has three months to prepare draft proposals on their identification as SVHCs and take a final decision in its committee procedure.